2024.05.06 Mooney Lymph Node paper

Press release title: Expanding a lymph node, boosting a vaccine Research Article: Durable lymph node expansion, softening, and cellular remodelling facilitate adaptive immunity after vaccination Journal: Nature Biomedical Engineering Lymph node staining 001: This immunofluorescent staining shows a lymph node that has been significantly expanded in mice with the help of the biomaterial MPS-vaccine (on the right), next to a lymph node taken from non-treated control mice (on the left) at the same time post-vaccination. Credit: Wyss Institute at Harvard University Lymph node composite: The authors used a method know as high-frequency ultrasound to monitor individual lymph nodes in MPS- and control-vaccinated mice. The top row shows a series of lymph nodes on day 7 following MPS vaccination. All of them were significantly expanded, compared to lymph nodes following control vaccination imaged at the same time and shown in the bottom row. Credit: Wyss Institute at Harvard University