dSHERLOCK

C. auris outbreaks_News Headlines – A series of Candida auris outbreaks in hospitals prompted the NY State Department of Health to release an urgent call to accelerate diagnostic developments that could help control future outbreaks. The Wyss team answered the call, received funding, and developed dSHERLOCK as a rapid and accurate diagnostic solution for the challenge. Credit: Wyss Institute at Harvard University dSHERLOCK_graphic abstract – As a precision diagnostic platform that combines CRISPR-based pathogen with single-molecule detection technology, dSHERLOCK enables the fast and quantitative assessment of fungal infections within 20 minutes and the presence of mutations that cause antifungal resistances within 40 minutes. In comparison, standard-of-care diagnostics testing can take days or weeks to identify an infection and are not able to determine resistances. Credit: Wyss Institute at Harvard University